Pipeline
Initially focused on musculoskeletal indications, our current pipeline includes programs for pain associated with knee osteoarthritis, lateral hip pain, thumb joint pain, and migraine.
Scroll to explore the pipeline.
| Indication |
Pre-ClinicalPilotPivotalCommercial Available |
|---|---|
| Pain Associated with Knee Osteoarthritis |
Pivotal clinical development |
| Lateral Hip Pain | Pivotal clinical development |
| Carpometacarpal (thumb) joint | Pilot clinical development |
| Migraine Disorders | Pre-clinical development |
Clinical Trials
A series of clinical studies are being conducted to evaluate the safety and effectiveness of Reneurx Nerve-Selective Therapy
Hip

Brixton is enrolling participants in the randomized, pivotal RENEU clinical trial evaluating the safety and effectiveness of Reneurx therapy for the management of chronic pain associated with the outer hip.
To qualify for RENEU, participants must meet the following eligibility criteria:
- Be between the age of 22 and 80 years old
- Experience outer hip pain on one or both hips
- Tried conservative therapies in the past that no longer provide relief
- Agree to see the study doctor for a 6 month follow up period, with the potential to be extended for 12 months
For additional information about trial, eligibility and trial locations, please visit: clinicaltrials.gov/study/NCT07568015.
Thumb
![]()
Brixton is conducting a pilot clinical study to evaluate the safety and effectiveness of Reneurx therapy in those with painful thumb basal joint arthritis.
To qualify, participants must meet the following eligibility criteria:
- Age of 22 years and older
- Have a diagnosis of carpometacarpal osteoarthritis
- Experience moderate thumb pain associated with use
- Have tried at least 6 months of other conservative treatments that no longer provide pain relief
For more information on the trial, eligibility, and trial locations, please contact: clinical@brixtonbio.com.